Theranostics: The future of nuclear medicine

Steven Larson (Memorial Sloan Kettering Cancer Center)
Event Date and Time: 
Wed, 2016-05-04 14:00 - 15:00
TRIUMF Auditorium

Theranostics is the use of the same molecular moiety for a combination of diagnosis and therapy. Radiotracers lend themselves to theranostics, because it is simply a matter of scaling up the dose, from diagnosis to therapy, in some important instances. A case in point would be the use of 124I for quantitative imaging, staging and diagnosis, in a patient who will subsequently be treated with 131I, for thyroid cancer. Other examples include the use of radiolabeled antibodies such as 124I-3F8 (an anti-GD2, antigen) at a low level for diagnosis, and then scaling up for therapeutic effect. PET imaging, and in some intstaces quantiative SPECT imaging, are the normal diagnostic imaging agents employed.

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