UBC Logo Steven Samuel Plotkin, Associate Professor at UBC
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Welcome to the website for the Plotkin Research Group!

We do research at the interface of biology and physics.

Our interests currently focus on the molecular-genetic study of the evolution of cellular differentiation, to the study of dynamics, disorder, and phase separation in the theory of protein folding, misfolding, and aggregation. Please see our Research Page for more details!

Dr. Steven Plotkin in his office

Plotkin Group News:

Recent Publications:

Recent Submissions:

  • Farrawell N, Yerbury M, Plotkin SS, McAlary L, Yerbury J "CuATSM Protects Against the Toxicity of Wild Type-like SOD1 Mutants But Not Mutants That Disrupt Metal Binding"
  • Peng X, Cashman NR and Plotkin SS "Prediction of Misfolding-Specific Epitopes in SOD1 Using Collective Coordinates"
  • Peng X, Gibbs, E, Silverman JM, Cashman NR, and Plotkin SS "A Method for Systematically Screening Drug Candidates Using Multiple Criteria with Unknown Predictive Importance"
  • Pataer A, Ozpolat, B, Shao R, Kabil, N, Lin S, Cashman NR, Samuel CE, Plotkin SS, Correa A, Majidi M, Fang B, Roth JA, Behrens C, Vaporciyan A, Wistuba I, Hung MC, Swisher S "PKR contributes to lysosome function, prevents misfolded protein release and is a target for cancer therapy"
  • Dupuis JH, Yu, H, Habibi M, Peng X, Plotkin SS, Wang S, Song C, Yada, RY "pH Dependant Membrane Binding of the Solanum tuberosum Plant Specific Insert"

We are grateful to the Canadian Institutes of Health Research, Alberta Innovates and the Alberta Prion Research Institute, and Westgrid/Compute Canada for supporting our research.

CIHR APRI Compute CanadaWestGrid















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