Welcome to the website for the Plotkin Research Group!

We do research at the interface of physics and biology.

Our interests range from the study of dynamics and disorder in the theory of protein folding, misfolding, and aggregation, to DNA function and dynamics, to studies of pattern formation and symmetry breaking in morphogenesis.

Plotkin Group News:

Will Guest graduated this May as the youngest MD/PhD in the Faculty of Medicine program's history--at age 25. News story. Video highlight.

Recently Published: UBC 6224 Agricultural Road

Mohazab AR, Plotkin SS "Polymer Uncrossing and Knotting in Protein Folding, and Their Role in Minimal Folding Pathways" PLoS ONE 8(1): e53642 (2013)

Das A, Plotkin SS "Mechanical Probes of SOD1 Predict Systematic Trends in Metal and Dimer Affinity of ALS-Associated Mutants" J. Mol. Biol. (2013) 425, 850–874

Das A, Plotkin SS "SOD1 Exhibits Allosteric Frustration to Facilitate Metal Binding Affinity" Proc. Natl. Acad. Sci. USA 110, 3871 (2013)

Chen S, Plotkin SS "Statistical Mechanics of Graph Models and their Implications for Emergent SpacetimeManifolds" Phys Rev D 87, 084011 (2013)

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