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UBC Logo Steven Samuel Plotkin, Associate Professor at UBC
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Welcome to the website for the Plotkin Research Group!

We do research at the interface of physics and biology.

Our interests range from the study of dynamics and disorder in the theory of protein folding, misfolding, and aggregation, to DNA function and dynamics, to studies of pattern formation and symmetry breaking in morphogenesis.

Dr. Steven Plotkin in his office

Plotkin Group News:

Recent Publications:

  • Silverman JM, Gibbs E, Martens KM, Balducci C, Peng X, Wang J, Yousefi M, Cowan CM, Lamour G, Louadi A, Ban Y, Robert J, Stukas S, Forloni G, Hsiung GR, Plotkin SS, Wellington CL and Cashman NR "A Synaptotoxic Aβ Oligomer Subclass Epitope Defined by Differential Orientation of a Single Amino Acid Side Chain," Submitted
  • Habibi M, Plotkin SS, and Rottler J "Soft Vibrational Modes Predict Force-induced Protein Unfolding Mechanisms" Submitted
  • Peng X, Gibbs, E, Silverman JM, Cashman NR, and Plotkin SS, "A Method for Systematically Screening Drug Candidates Using Multiple Criteria with Unknown Predictive Importance" Submitted
  • Habibi M, Rottler J, and Plotkin SS "The Unfolding Mechanism of Monomeric Mutant SOD1 by Simulated Force Spectroscopy", Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, https://doi.org/10.1016/j.bbapap.2017.06.009 (2017)
  • Habibi M, Rottler J, and Plotkin SS "As Simple as Possible but not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy", PLoS Comput Biol 12(11): e1005211. doi:10.1371/journal. pcbi.1005211. (2016)

 

 

 

 

 

 

 

 

 

 

 

 

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